SecureBio Detection is a nonprofit building the world's largest metagenomic biosurveillance network for pathogen detection. They are hiring for two senior roles: an infrastructure engineer and a software engineer for high-performance data pipelines. The roles focus on processing deep sequencing data and managing cloud infrastructure for their pathogen screening network.
A starter prompt for Claude Code, what you'll need, and how to reach them.
You are a senior infrastructure and data pipeline engineer. SecureBio Detection is a non-profit operating the world's largest metagenomic biosurveillance network. They are hiring for two roles: Senior infrastructure engineer (cloud infra, DevOps, CI/CD, AWS security) and Senior software engineer (high-performance data pipelines). The core task is to process deep sequencing data rapidly to flag pathogens. Your goal is to propose a detailed, high-level architecture and a concrete 2-week MVP for a component of their data pipeline that demonstrates expertise in both infrastructure and high-performance processing. Focus on AWS as the cloud provider. Use Next.js 16 App Router, React 19, Tailwind v4 for any potential dashboard/monitoring component, and Python/Rust for the backend processing logic. Employ AI SDK v6 with Gemini for generating any synthetic data or documentation. Store metadata in Neon Postgres and raw/processed data in S3. Your MVP should demonstrate secure ingestion and initial processing of a simulated 'wastewater sample' dataset. MVP to ship: a serverless function that accepts a simulated raw sequencing data payload (e.g., a FASTA file URL in S3), performs a basic quality check (simulated), and stores metadata about the sample and its quality in Neon Postgres. Build/verify gate: A working serverless endpoint that can be invoked with a sample data pointer, logs the simulated processing, and records a new entry in a Postgres database.
SecureBio Detection | Senior infrastructure engineer; [senior] software engineer (high-performance pipelines) Cambridge, MA, USA (metro Boston) | ONSITE strongly preferred; REMOTE (US east coast) possible for exceptional candidates SecureBio is a nonprofit working to protect the world from catastrophic pandemics. We operate the world’s largest metagenomic biosurveillance network, which performs daily sequencing of wastewater samples and nasal swabs to screen for emerging pathogens. Our computational team develops detection pipelines responsible for rapid processing of deep sequencing data in order to flag potential threats. I'm the hiring manager for two roles: - Senior infrastructure engineer, to own cloud infra, devops, CI/CD, AWS security, etc. Job posting should be up by this time tomorrow. - [Senior] software engineer focused on high performance data pipelines. https://securebio.org/careers/2026-software-engineer-pipelin... Prior experience with biology or bioinformatics is not required. If you're interested, feel free to drop me a line; email is in my profile. https://securebio.org/careers/
Email the hiring manager (Tarrosion) directly using the email in their Hacker News profile.
“I'm a solo operator specializing in high-performance, secure cloud data pipelines. I've analyzed your roles at SecureBio Detection and can deliver an architecture and MVP demonstrating secure data ingestion and processing, addressing your need for rapid pathogen detection. I've attached a high-level proposal; let's discuss how I can contribute.”
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